![]() Little is known about the biological contributions to the development of depressive symptoms in PWH. ![]() ![]() People with HIV (PWH) disproportionately experience depression, which increases their risk for poor viral control, cognitive impairment, and death, and affects the rate at which they seek medical care. Interventions that target OT/CRP and MM factors may alter social processing for PWH including ELT-exposed individuals. A myeloid migration (MM) factor was associated with reduced social processing accuracy regardless of ELT. An OT/C-reactive protein (CRP) factor moderated ELT-performance associations, indicating a potential role of inflammation-related processes. examined secondary data to find that social processing difficulties and higher oxytocin (OT) levels were more common in people living with HIV (PWH) who were exposed to ELT compared to ELT-unexposed PWH. ![]() These findings support an active-interference model for risk of depression.Įarly life trauma (ELT) and HIV infection are associated with social processing deficits. In contrast, the results in this study indicated higher activation in this region when participants were tasked with attending to their heartbeat while ignoring a distracting tone. Hypoactivity of the anterior insula has previously been reported in individuals with major depression. in a diverse sample of postmenopausal women with and without HIV. The neural dynamics underlying cardiac interoceptive awareness and its relationship to depressive symptom severity were investigated by Roger McIntosh et al. In an introductory article, Guest Editors Adam Carrico, Leah Rubin, and Robert Paul provide an outline of the themes covered in this special issue “Biobehavioral and Neurobehavioral Processes in the HIV–Mental Health Interaction.” In addition, PWH commonly experience stigma and other psychosocial stressors that are linked to neuroendocrine stress responses, potentiate residual immune system dysregulation, and alter other biobehavioral processes relevant to health outcomes. People with HIV (PWH) receiving effective ART often continue to display residual immune system dysregulations that may amplify the risk for neurological and psychiatric comorbidities thereby adversely affecting their mental health. This special issue of Psychosomatic Medicine addresses the intersection of HIV with mental health in the modern era of antiretroviral therapy (ART). ![]()
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |